In vivo Iron-Based Coordination Assembly for Disease Diagnosis and Treatment

doi:10.15212/bioi-2022-0016

Residential College	false
Status	已發表Published
	In vivo Iron-Based Coordination Assembly for Disease Diagnosis and Treatment
	Lin, Gan 1; Lin, Huirong 1; Yuan, Zhen 2; Liu, Gang 1
	2023
Source Publication	BIO Integration
Volume	4 Issue:2 Pages:70-72
Abstract	Advances in in vivo iron-based coordination assembly have enabled the simultaneous detection and treatment of iron-overload disorders. Specific interactions between local Fe and organic ligands (e.g., indocyanine green and lecithin) facilitate magnetic resonance imaging with enhanced sensitivity and photoacoustic imaging with high contrast, thus overcoming the longstanding limitations of traditional iron quantification approaches. Moreover, enhanced iron depletion can also be achieved in murine genetic models of iron-overload disorders. These advances provide great promise in interdisciplinary leveraging of biology, medicine and materials science to design nanomedicines for addressing unmet clinical needs.
Keyword	In Vivo Assembly Iron-based Coordination Assembly Multimodal Molecular Imaging Theranostics
DOI	10.15212/bioi-2022-0016
URL	View the original
Language	英語English
Publisher	Compuscript Ltd
Scopus ID	2-s2.0-85174283260
Fulltext Access	View Full-Text via DOI View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	University of Macau Faculty of Health Sciences
Corresponding Author	Liu, Gang
Affiliation	1.State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361102, China 2.Faculty of Health Sciences, University of Macau, 999078, Macao
Recommended Citation GB/T 7714	Lin, Gan,Lin, Huirong,Yuan, Zhen,et al. In vivo Iron-Based Coordination Assembly for Disease Diagnosis and Treatment[J]. BIO Integration, 2023, 4(2), 70-72.
APA	Lin, Gan., Lin, Huirong., Yuan, Zhen., & Liu, Gang (2023). In vivo Iron-Based Coordination Assembly for Disease Diagnosis and Treatment. BIO Integration, 4(2), 70-72.
MLA	Lin, Gan,et al."In vivo Iron-Based Coordination Assembly for Disease Diagnosis and Treatment".BIO Integration 4.2(2023):70-72.

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