Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis

doi:10.1016/j.chmed.2023.03.003

Residential College	false
Status	已發表Published
	Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis
	Yang, Yifei 1,2; Wang, Yi 3; Zhao, Long 4; Wang, Fang 1,2; Li, Mingxing 1,2,5; Wang, Qin 1,2; Luo, Haoming 1,2; Zhao, Qianyun 1,2; Zeng, Jiuping 1,2; Zhao, Yueshui 1,2,5; Du, Fukuan 1,2,5; Chen, Yu 1,2,5; Shen, Jing 1,2,5; Wei, Shulin 1,2; Xiao, Zhangang 1,2,5; Wu, Xu 1,2,5,6
	2023-04-01
Source Publication	Chinese Herbal Medicines
ISSN	1674-6384
Volume	15 Issue:2 Pages:181-200
Abstract	Ulcerative colitis (UC) is one of types of inflammatory bowel disease with high recurrence. Recent studies have highlighted that microbial dysbiosis as well as abnormal gut immunity are crucial factors that initiate a series of inflammatory responses in the UC. Modulating the gut microbiota-intestinal immunity loop has been suggested as one of key strategies for relieving UC. Many Chinese herbal medicines including some of single herb, herbal formulas and the derived constituents have been reported with protective effect against UC through modulating gut microbiome and intestinal immunity. Some clinical trials have shown promising results. This review thus focused on the current knowledge on using Chinese herbal medicines for treating UC from the mechanism aspects of regulating intestinal homeostasis involving microbiota and gut immunity. The existing clinical trials are also summarized.
Keyword	Chinese herbal medicines gut microbiota inflammation inflammatory bowel disease intestinal immunity ulcerative colitis
DOI	10.1016/j.chmed.2023.03.003
URL	View the original
Language	英語English
Scopus ID	2-s2.0-85151399035
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics
Document Type	Journal article
Collection	University of Macau
Affiliation	1.Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, 646000, China 2.Luzhou Key Laboratory of Cell Therapy & Cell Drugs, Luzhou, 646000, China 3.Sichuan Fifth People's Hospital, Chengdu, 610015, China 4.Department of Spleen and Stomach Diseases, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, 646000, China 5.South Sichuan Institute of Translational Medicine, Luzhou, 646000, China 6.State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao, 999078, China
Recommended Citation GB/T 7714	Yang, Yifei,Wang, Yi,Zhao, Long,et al. Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis[J]. Chinese Herbal Medicines, 2023, 15(2), 181-200.
APA	Yang, Yifei., Wang, Yi., Zhao, Long., Wang, Fang., Li, Mingxing., Wang, Qin., Luo, Haoming., Zhao, Qianyun., Zeng, Jiuping., Zhao, Yueshui., Du, Fukuan., Chen, Yu., Shen, Jing., Wei, Shulin., Xiao, Zhangang., & Wu, Xu (2023). Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis. Chinese Herbal Medicines, 15(2), 181-200.
MLA	Yang, Yifei,et al."Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis".Chinese Herbal Medicines 15.2(2023):181-200.

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