Aim/purpose - Cultural differences play an influential role in driving tourism development and varying outcomes of technology acceptance. The impact of ChatGPT on tourism is yet to be explored. Therefore, this study discussed how ChatGPT may influence tourism development and management in different cultural contexts. Design/methodology/approach - Drawing specifically on individualism and collectivism from Hofstede's cultural dimensions theory, this study compared the differences in the perception of ChatGPT between Oriental and Western cultures. Findings - Individualism and collectivism explain the diversity of perception on ChatGPT between Oriental and Western cultures. Research implications/limitations - Implications and suggestions are provided to academia and industry accordingly. Particularly, the difference between technological concepts and tools is highlighted to avoid having excessive expectations toward tools. Originality/value/contribution - This study extends the research on tourism and Artificial Intelligence and advocates additional attention to the imperative of cross-cultural differences regarding ChatGPT and tourism.