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CERS4 predicts positive anti-PD-1 response and promotes immunomodulation through Rhob-mediated suppression of CD8+Tim3+ exhausted T cells in non-small cell lung cancer.
Wang Jian1,2; Li RunZe3,4; Wang WenJun5; Pan HuDan3,4; Xie Chun6; Yau LeeFong1; Wang XingXia1; Long WeiLi7; Chen RuiHong1; Liang TuLiang3; Ma LinRui1; Li JiaXin1; Huang JuMin6; Wu QiBiao1; Liu Liang3,4; He JianXing5; Leung Elaine Lai Han6,8
2023-08
Source PublicationPharmacological Research
Document TypeJournal article
CollectionINSTITUTE OF COLLABORATIVE INNOVATION
Corresponding AuthorLiu Liang; He JianXing; Leung Elaine Lai Han
Affiliation1.Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery/State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Macau (SAR), China
2.Department of Medical Oncology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu, China
3.State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
4.Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research, Guangzhou, China
5.State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
6.Cancer Center, Faculty of Health Sciences, University of Macau, Macau (SAR), China. MOE Frontiers Science Center for Precision Oncology, University of Macau, Macau (SAR), China. State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau (SAR), China
7.Department of Oncology, Luzhou People's Hospital, Luzhou, Sichuan, China
8.Laboratory of Allergy and Precision Medicine, Chengdu Institute of Respiratory Health, the Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, China; Department of Pulmonary and Critical Care Medicine, Chengdu Institute of Respiratory Health, Chengdu Third People's Hospital Branch of National Clinical Research Center for Respiratory Disease, Chengdu, China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationCancer Centre
Recommended Citation
GB/T 7714
Wang Jian,Li RunZe,Wang WenJun,et al. CERS4 predicts positive anti-PD-1 response and promotes immunomodulation through Rhob-mediated suppression of CD8+Tim3+ exhausted T cells in non-small cell lung cancer.[J]. Pharmacological Research, 2023.
APA Wang Jian., Li RunZe., Wang WenJun., Pan HuDan., Xie Chun., Yau LeeFong., Wang XingXia., Long WeiLi., Chen RuiHong., Liang TuLiang., Ma LinRui., Li JiaXin., Huang JuMin., Wu QiBiao., Liu Liang., He JianXing., & Leung Elaine Lai Han (2023). CERS4 predicts positive anti-PD-1 response and promotes immunomodulation through Rhob-mediated suppression of CD8+Tim3+ exhausted T cells in non-small cell lung cancer.. Pharmacological Research.
MLA Wang Jian,et al."CERS4 predicts positive anti-PD-1 response and promotes immunomodulation through Rhob-mediated suppression of CD8+Tim3+ exhausted T cells in non-small cell lung cancer.".Pharmacological Research (2023).
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