| Residential College | false |
| Patent Number | CN114042154A |
| Status | 申請中 Pending |
| 一種藥物組合在製備抗腫瘤的聯合治療藥物中的應用 Application of a drug combination in the preparation of anticancer combination therapy drugs | |
| Year Issued | 2022 |
| 2022-02 | |
| Application Number | 202111525685.8 |
Lu, Jinjian  ; Huang, Canyu
| |
| Country | China |
| Subtype | 发明专利 Invention |
| Abstract | 本發明公開了一種藥物組合在製備抗腫瘤的聯合治療藥物中的應用，涉及生物醫藥技術領域。藥物組合包括：抑制PD‑1或抑制PD‑L1的多肽和/或抗體、和中藥成分；中藥成分為石蒜堿或其鹽，或其水合物。發明人發現中藥成分石蒜堿聯合抑制PD‑1或抑制PD‑L1的多肽和/或抗體在體內獲得了協同增效的抗腫瘤效果，並顯著改善了免疫微環境。這為製備抗腫瘤的聯合治療藥物提供了有利前提，也將是聯合增強PD‑1/PD‑L1抗體一個具有潛力的策略。 |
| Document Type | Patent |
| Collection | Institute of Chinese Medical Sciences |
| Corresponding Author | Lu, Jinjian |
| Affiliation | University of Macau |
| First Author Affilication | University of Macau |
| Recommended Citation GB/T 7714 | Lu, Jinjian,Huang, Canyu. 一種藥物組合在製備抗腫瘤的聯合治療藥物中的應用 Application of a drug combination in the preparation of anticancer combination therapy drugs. CN114042154A[P]. 2022-02-01. |
| APA | Lu, Jinjian., & Huang, Canyu 一種藥物組合在製備抗腫瘤的聯合治療藥物中的應用 Application of a drug combination in the preparation of anticancer combination therapy drugs. |
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