Mining prognosis index of brain metastases using artificial intelligence

UM > Faculty of Science and Technology > DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE

Status	已發表Published
	Mining prognosis index of brain metastases using artificial intelligence
	Huang, S.; Yang, J.; Fong, S.; Zhao, Q.
	2019-08-09
Source Publication	Cancers
ISSN	2072-6694
Pages	1140-1140
Abstract	This study is to identify the optimum prognosis index for brain metastases by machine learning. Seven hundred cancer patients with brain metastases were enrolled and divided into 446 training and 254 testing cohorts. Seven features and seven prediction methods were selected to evaluate the performance of cancer prognosis for each patient. We used mutual information and rough set with particle swarm optimization (MIRSPSO) methods to predict patient’s prognosis with the highest accuracy at area under the curve (AUC) = 0.978 ± 0.06. The improvement by MIRSPSO in terms of AUC was at 1.72%, 1.29%, and 1.83% higher than that of the traditional statistical method, sequential feature selection (SFS), mutual information with particle swarm optimization(MIPSO), and mutual information with sequential feature selection (MISFS), respectively. Furthermore, the clinical performance of the best prognosis was superior to conventional statistic method in accuracy, sensitivity, and specificity. In conclusion, identifying optimal machine-learning methods for the prediction of overall survival in brain metastases is essential for clinical applications. The accuracy rate by machine-learning is far higher than that of conventional statistic methods.
Keyword	brain metastases radiosurgery prognosis index artificial intelligence
URL	View the original
Language	英語English
The Source to Article	PB_Publication
PUB ID	45915
Document Type	Journal article
Collection	DEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Corresponding Author	Fong, S.; Zhao, Q.
Recommended Citation GB/T 7714	Huang, S.,Yang, J.,Fong, S.,et al. Mining prognosis index of brain metastases using artificial intelligence[J]. Cancers, 2019, 1140-1140.
APA	Huang, S.., Yang, J.., Fong, S.., & Zhao, Q. (2019). Mining prognosis index of brain metastases using artificial intelligence. Cancers, 1140-1140.
MLA	Huang, S.,et al."Mining prognosis index of brain metastases using artificial intelligence".Cancers (2019):1140-1140.

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