Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2

UM > Faculty of Health Sciences > DEPARTMENT OF BIOMEDICAL SCIENCES

Status	已發表Published
	Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2
	Zhou, G.; Zhao, Q.
	2020-03-15
Source Publication	International Journal of Biological Sciences
ISSN	1449-2288
Pages	1718-1723
Abstract	A newly identified novel coronavirus (SARS-CoV-2) is causing pneumonia-associated respiratory syndrome across the world. Epidemiology, genomics, and pathogenesis of the SARS-CoV-2 show high homology with that of SARS-CoV. Current efforts are focusing on development of specific antiviral drugs. Therapeutic neutralizing antibodies (NAbs) against SARS-CoV-2 will be greatly important therapeutic agents for the treatment of coronavirus disease 2019 (COVID-19). Herein, the host immune responses against SARS-CoV discussed in this review provide implications for developing NAbs and understanding clinical interventions against SARS-CoV-2. Further, we describe the benefits, challenges and considerations of NAbs against SARS-CoV-2. Although many challenges exist, NAbs still offer a therapeutic option to control the current pandemic and the possible re-emergence of the virus in the future, and their development therefore remains a high priority.
Keyword	COVID-19 Neutralizing antibody SARS-CoV-2 severe acute respiratory syndrome
URL	View the original
Language	英語English
The Source to Article	PB_Publication
PUB ID	52272
Document Type	Journal article
Collection	DEPARTMENT OF BIOMEDICAL SCIENCES
Corresponding Author	Zhao, Q.
Recommended Citation GB/T 7714	Zhou, G.,Zhao, Q.. Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2[J]. International Journal of Biological Sciences, 2020, 1718-1723.
APA	Zhou, G.., & Zhao, Q. (2020). Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2. International Journal of Biological Sciences, 1718-1723.
MLA	Zhou, G.,et al."Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2".International Journal of Biological Sciences (2020):1718-1723.

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