Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin

UM > Faculty of Health Sciences > DEPARTMENT OF BIOMEDICAL SCIENCES

Status	已發表Published
	Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin
	Tang, Y.; Liang, T.; Fan, T.; Keen, L.; Zhang, X.; Xu, L.; Zhao, Q.; Zeng, R.; Han, B.
	2020-08-01
Source Publication	Natural Product Research
ISSN	1478-6419
Pages	2151-2156
Abstract	Neo-debromoaplysiatoxin C (1), a new member of the aplysiatoxin family, was isolated from the marine cyanobacterium Lyngbya sp. The structure of 1 was elucidated based on spectroscopic data, and its stereochemistry was determined from NOESY spectrum and biosynthetic considerations. This new compound presents an intriguing 10-membered lactone ring skeleton derived from debromoaplysiatoxin by structural rearrangement, which is the first example in the aplysiatoxin family. Its biological properties were evaluated for cytotoxicity, PKCδ activation and inhibitory effects on potassium channel.
Keyword	Neo-debromoaplysiatoxin C debromoaplysiatoxin newly discovered structural frame Lyngbya sp
URL	View the original
Language	英語English
The Source to Article	PB_Publication
PUB ID	45913
Document Type	Journal article
Collection	DEPARTMENT OF BIOMEDICAL SCIENCES
Corresponding Author	Han, B.
Recommended Citation GB/T 7714	Tang, Y.,Liang, T.,Fan, T.,et al. Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin[J]. Natural Product Research, 2020, 2151-2156.
APA	Tang, Y.., Liang, T.., Fan, T.., Keen, L.., Zhang, X.., Xu, L.., Zhao, Q.., Zeng, R.., & Han, B. (2020). Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin. Natural Product Research, 2151-2156.
MLA	Tang, Y.,et al."Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin".Natural Product Research (2020):2151-2156.

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