With the development of modern agriculture, the pursuit of crop yields has led to various pollution problems, including excessive pesticide residue that endangers human safety. Specifically, in the context of Chinese herbal medicine, the detrimental impact of pesticide residues has significantly hampered the international import and export trade of such commodities.  In addition, conventional detection methods have the disadvantages of high detection costs, high technical requirements, and complex sample preparation. Therefore, it is urgent to develop a portable, environmentally friendly, simple and rapid detection strategy. In this regard, we proposed a rapid detection strategy for the residues of organophosphorus pesticides. The pesticide-contaminated samples were treated with highly catalytically active nanozyme, and the pesticide degradation products were quickly quantified using a composite ratiometric fluorescent probe. The fluorescent probe has dual signal sources. The blue color signal is used for detection, and the orange color signal is used as a reference. The sensing mechanism is based on the selective quenching of the blue color signal from the probes by ultra-violet absorption of the degraded product. In contrast, the orange color signal of probes is relatively unaffected. After verification, the method has good sensitivity, selectivity and repeatability. Further, the designed detection strategy can be accurately quantified in complex matrices (Ginseng Radix et Rhizoma, Coicis Semen and tap water). All in all, the method proposed a new strategy for the safety evaluation of Chinese herbal medicine, and provided a reference for the pollution evaluation of pesticide residues.