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The Effectiveness of Electrical Vestibular Stimulation (VeNS) on Symptoms of Anxiety: Study Protocol of a Randomized, Double-Blinded, Sham-Controlled Trial
Cheung, Teris1,2; Lam, Joyce Yuen Ting1; Fong, Kwan Hin1; Ho, Yuen Shan1; Ho, Alex3; Cheng, Calvin Pak Wing4; Sittlington, Julie5; Xiang, Yu Tao6; Li, Tim Man Ho7
2023-03-01
Source PublicationInternational Journal of Environmental Research and Public Health
ISSN1660-4601
Volume20Issue:5Pages:4218
Abstract

The prevalence of symptoms of anxiety is increasing, especially during the COVID-19 pandemic. A home use transdermal neurostimulation device might help to minimize the severity of anxiety disorder. To the best of our knowledge, there is no clinical trial using transdermal neurostimulation to treat individuals with symptoms of anxiety in Asia. This gives us the impetus to execute the first study which aims at evaluating the efficacy of Electrical Vestibular Stimulation (VeNS) on anxiety in Hong Kong. This study proposes a two-armed, double-blinded, randomized, sham-controlled trial including the active VeNS and sham VeNS group. Both groups will be measured at baseline (T1), immediately after the intervention (T2), and at the 1-month (T3) and 3-month follow-up (T4). A total of 66 community-dwelling adults aged 18 to 60 with anxiety symptoms will be recruited in this study. All subjects will be computer randomised into either the active VeNS group or the sham VeNS group in a 1:1 ratio. All subjects in each group will receive twenty 30 min VeNS sessions during weekdays, which will be completed in a 4-week period. Baseline measurements and post-VeNS evaluation of the psychological outcomes (i.e., anxiety, insomnia, and quality of life) will also be conducted on all participants. The 1-month and 3-month follow-up period will be used to assess the long-term sustainability of the VeNS intervention. For statistical analysis, ANOVA with repeated measures will be used to analyze data. Missing data were managed with multiple mutations. The level of significance will be set to p < 0.05. Results of this study will be used to determine whether this VeNS device can be considered as a self-help technological device to reduce perceived anxiety in the general population in the community setting. This clinical Trial was registered with the Clinical Trial government, identifier: NCT04999709.

KeywordVestibular Stimulation Rct Anxiety Non-invasive Brain Stimulation Efficacy
DOI10.3390/ijerph20054218
URLView the original
Language英語English
Scopus ID2-s2.0-85150153681
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Document TypeJournal article
CollectionDEPARTMENT OF PUBLIC HEALTH AND MEDICINAL ADMINISTRATION
Faculty of Health Sciences
Corresponding AuthorCheung, Teris; Li, Tim Man Ho
Affiliation1.School of Nursing, The Hong Kong Polytechnic University, Hong Kong SAR, China
2.The Mental Health Research Centre, The Hong Kong Polytechnic University, Hong Kong SAR, China
3.Integrated Services for Persons with Disabilities, Christian Family Service Centre, Hong Kong SAR, China
4.Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China
5.School of Biomedical Sciences, Ulster University, Coleraine, BT52 1SA, United Kingdom
6.Department of Public Health and Medicinal Administration, Faculty of Health Sciences, University of Macau, Macau SAR, China
7.Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China
Recommended Citation
GB/T 7714
Cheung, Teris,Lam, Joyce Yuen Ting,Fong, Kwan Hin,et al. The Effectiveness of Electrical Vestibular Stimulation (VeNS) on Symptoms of Anxiety: Study Protocol of a Randomized, Double-Blinded, Sham-Controlled Trial[J]. International Journal of Environmental Research and Public Health, 2023, 20(5), 4218.
APA Cheung, Teris., Lam, Joyce Yuen Ting., Fong, Kwan Hin., Ho, Yuen Shan., Ho, Alex., Cheng, Calvin Pak Wing., Sittlington, Julie., Xiang, Yu Tao., & Li, Tim Man Ho (2023). The Effectiveness of Electrical Vestibular Stimulation (VeNS) on Symptoms of Anxiety: Study Protocol of a Randomized, Double-Blinded, Sham-Controlled Trial. International Journal of Environmental Research and Public Health, 20(5), 4218.
MLA Cheung, Teris,et al."The Effectiveness of Electrical Vestibular Stimulation (VeNS) on Symptoms of Anxiety: Study Protocol of a Randomized, Double-Blinded, Sham-Controlled Trial".International Journal of Environmental Research and Public Health 20.5(2023):4218.
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