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Semantic-Powered Explainable Model-Free Few-Shot Learning Scheme of Diagnosing COVID-19 on Chest X-Ray
Wang, Yihang1; Jiang, Chunjuan3; Wu, Youqing1; Lv, Tianxu1; Sun, Heng2; Liu, Yuan1; Li, Lihua4; Pan, Xiang1,2
2022-12-01
Source PublicationIEEE Journal of Biomedical and Health Informatics
ISSN2168-2194
Volume26Issue:12Pages:5870-5882
Abstract

Chest X-ray (CXR) is commonly performed as an initial investigation in COVID-19, whose fast and accurate diagnosis is critical. Recently, deep learning has a great potential in detecting people who are suspected to be infected with COVID-19. However, deep learning resulting with black-box models, which often breaks down when forced to make predictions about data for which limited supervised information is available and lack inter-pretability, still is a major barrier for clinical integration. In this work, we hereby propose a semantic-powered explainable model-free few-shot learning scheme to quickly and precisely diagnose COVID-19 with higher reliability and transparency. Specifically, we design a Report Image Explanation Cell (RIEC) to exploit clinically indicators derived from radiology reports as interpretable driver to introduce prior knowledge at training. Meanwhile, multi-task collaborative diagnosis strategy (MCDS) is developed to construct ${\boldsymbol{N}}$-way ${\boldsymbol{K}}$-shot tasks, which adopts a cyclic and collaborative training approach for producing better generalization performance on new tasks. Extensive experiments demonstrate that the proposed scheme achieves competitive results (accuracy of 98.91%, precision of 98.95%, recall of 97.94% and F1-score of 98.57%) to diagnose COVID-19 and other pneumonia infected categories, even with only 200 paired CXR images and radiology reports for training. Furthermore, statistical results of comparative experiments show that our scheme provides an interpretable window into the COVID-19 diagnosis to improve the performance of the small sample size, the reliability and transparency of black-box deep learning models. Our source codes will be released on https://github.com/AI-medical-diagnosis-team-of-JNU/SPEMFSL-Diagnosis-COVID-19.

KeywordChest X-ray Covid-19 ExplAinable Ai Few-shot Learning Semantic-powered
DOI10.1109/JBHI.2022.3205167
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaComputer Science ; Mathematical & Computational Biology ; Medical Informatics
WOS SubjectComputer Science, Information Systems ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Medical Informatics
WOS IDWOS:000894943300012
PublisherIEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 445 HOES LANE, PISCATAWAY, NJ 08855-4141
Scopus ID2-s2.0-85137854122
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
Cancer Centre
Corresponding AuthorJiang, Chunjuan; Pan, Xiang
Affiliation1.School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi 214122, China
2.Cancer Centre, Faculty of Health Sciences, University of Macau, Macau SAR 999078, China
3.Department of Nuclear Medicine/PET Image Center, The Second Xiangya Hospital of Central South University, Changsha 410011, China
4.Institute of Biomedical Engineering and Instrumentation, Hangzhou Dianzi University, Hangzhou 310018, China
Corresponding Author AffilicationCancer Centre
Recommended Citation
GB/T 7714
Wang, Yihang,Jiang, Chunjuan,Wu, Youqing,et al. Semantic-Powered Explainable Model-Free Few-Shot Learning Scheme of Diagnosing COVID-19 on Chest X-Ray[J]. IEEE Journal of Biomedical and Health Informatics, 2022, 26(12), 5870-5882.
APA Wang, Yihang., Jiang, Chunjuan., Wu, Youqing., Lv, Tianxu., Sun, Heng., Liu, Yuan., Li, Lihua., & Pan, Xiang (2022). Semantic-Powered Explainable Model-Free Few-Shot Learning Scheme of Diagnosing COVID-19 on Chest X-Ray. IEEE Journal of Biomedical and Health Informatics, 26(12), 5870-5882.
MLA Wang, Yihang,et al."Semantic-Powered Explainable Model-Free Few-Shot Learning Scheme of Diagnosing COVID-19 on Chest X-Ray".IEEE Journal of Biomedical and Health Informatics 26.12(2022):5870-5882.
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