Residential College | false |
Status | 已發表Published |
An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing | |
Zheng, Lu1; Gu, Bin1; Li, Shanshan1; Luo, Bichong1; Wen, Yuming1; Chen, Meiwan2; Li, Xiaoyun1; Zha, Zhengang3; Zhang, Huan Tian3; Wang, Xiaoying1 | |
2022-11-15 | |
Source Publication | Carbohydrate Polymers |
ISSN | 0144-8617 |
Volume | 296Pages:119924 |
Abstract | The development of shape-memory sponge dressings with functions, such as hemostasis, antibacterial activity, and wound healing, is of great significance in clinical applications. Herein, a novel AuNPs@corn stalk/chitin composite sponge (CCAu) was fabricated by crosslinking the chitin matrix with corn stalk-embedded gold nanoparticles (AuNPs). The addition of AuNPs@corn stalk gave the porous chitin sponge shape-recovery ability with improved softness, porosity, and water absorption. Correspondingly, the composite sponge showed better hemostatic effects than commercial PVF sponges. The photothermal effect of AuNPs endowed the composite sponge with excellent antibacterial activity. In addition, the wound treated with composite sponge containing antioxidant AuNPs exhibited a significantly faster wound healing rate (reaching 41.6 % on day 3) than the CH (33.2 %) and control (12.6 %) group through promoting cell migration, angiogenesis and collagen deposition. Therefore, the multifunctional composite sponge with great biocompatibility in this work provides a potential strategy for wound healing. |
Keyword | Chitin Sponge Aunps@corn Stalk Shape-recovery Photothermal Antibacterial Effect Hemostatic Sponge Wound Healing |
DOI | 10.1016/j.carbpol.2022.119924 |
URL | View the original |
Indexed By | SCIE |
Language | 英語English |
WOS Research Area | Chemistry ; Polymer Science |
WOS Subject | Chemistry, Applied ; Chemistry, Organic ; Polymer Science |
WOS ID | WOS:000843937700002 |
Publisher | ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
Scopus ID | 2-s2.0-85135389160 |
Fulltext Access | |
Citation statistics | |
Document Type | Journal article |
Collection | THE STATE KEY LABORATORY OF QUALITY RESEARCH IN CHINESE MEDICINE (UNIVERSITY OF MACAU) Institute of Chinese Medical Sciences |
Corresponding Author | Li, Xiaoyun; Zhang, Huan Tian |
Affiliation | 1.State Key Laboratory of Pulp & Paper Engineering, South China University of Technology, Guangzhou, 510640, China 2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China 3.Department of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China |
Recommended Citation GB/T 7714 | Zheng, Lu,Gu, Bin,Li, Shanshan,et al. An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing[J]. Carbohydrate Polymers, 2022, 296, 119924. |
APA | Zheng, Lu., Gu, Bin., Li, Shanshan., Luo, Bichong., Wen, Yuming., Chen, Meiwan., Li, Xiaoyun., Zha, Zhengang., Zhang, Huan Tian., & Wang, Xiaoying (2022). An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing. Carbohydrate Polymers, 296, 119924. |
MLA | Zheng, Lu,et al."An antibacterial hemostatic AuNPs@corn stalk/chitin composite sponge with shape recovery for promoting wound healing".Carbohydrate Polymers 296(2022):119924. |
Files in This Item: | There are no files associated with this item. |
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment