We examine the degree to which an individual's religious involvement significantly mediates and buffers the effects of neighborhood disorder on youth crime. To test this hypothesis, we analyzed the fifth wave of data from the National Youth Survey, focusing on black respondents given the historical as well as contemporary significance of the African-American church for black Americans. Results from estimating a series of regression models indicated that (1) the effects of neighborhood disorder on crime among black youth are partly mediated by an individual's religious involvement (measured by the frequency of attending religious services) and (2) involvement of African-American youth in religious institutions significantly buffers or interacts with the effects of neighborhood disorder on crime and, in particular, serious crime. Theoretical and methodological implications of the present findings are briefly discussed.