天然产物是生物在自然界长期进化和生长过程中不断被选择和优化的结果。由于其具有独特的化学结构和良好的生物活性，天然产物是新药设计和研发的重要源泉。随着社会经济和科学技术的不断发展，天然产物化学的研究手段取得了较大的进展。本文对天然产物的提取分离技术进行总结，以期为天然产物的化学研究提供参考和思路。Natural products are synthesized for the fitness of the environment during evolution. Natural products play an important role in new drug development due to their unique chemical structures and more drug-like properties. With the continuous developments of related techniques, the research of natural product chemistry has made great progress. In this paper, the methods of extraction and separation of natural products are summarized, which may provide references and ideas for the chemical research of natural products and the discovery of new drugs.