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Understanding MicroRNA regulation: A computational perspective
Yue D.2; Meng J.2; Lu M.2; Chen C.L.P.2; Guo M.3; Huang Y.2
2012
Source PublicationIEEE Signal Processing Magazine
ISSN10535888
Volume29Issue:1Pages:77-88
Abstract

Our knowledge of gene regulators presents an intrinsically unbalanced picture inadequate to fully explain the great complexity of their cellular functions. It is now understood that gene regulation assumes multiple modes including transcriptional regulation by transcription factors (TFs) and the posttranscriptional regulation by microRNA (miRNA). MiRNA is a class of small noncoding RNAs of ,22 nucleotides. It is known to repress transcription and/or inhibit translation of a large number of genes by binding mainly to the 3r untranslated region (UTR) of target genes [1], [2]. Elucidating specific functions of miRNAs comprises one of the most active research areas. ©2012 IEEE.

DOI10.1109/MSP.2011.943013
URLView the original
Language英語English
WOS IDWOS:000298295900010
Scopus ID2-s2.0-85032751589
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Citation statistics
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Society of Operations Research
2.University of Texas at San Antonio
3.Harbin Institute of Technology
Recommended Citation
GB/T 7714
Yue D.,Meng J.,Lu M.,et al. Understanding MicroRNA regulation: A computational perspective[J]. IEEE Signal Processing Magazine, 2012, 29(1), 77-88.
APA Yue D.., Meng J.., Lu M.., Chen C.L.P.., Guo M.., & Huang Y. (2012). Understanding MicroRNA regulation: A computational perspective. IEEE Signal Processing Magazine, 29(1), 77-88.
MLA Yue D.,et al."Understanding MicroRNA regulation: A computational perspective".IEEE Signal Processing Magazine 29.1(2012):77-88.
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