| Residential College | false |
| Status | 已發表Published |
| Synthesis and Evaluation of O2‑Derived Diazeniumdiolates Activatable via Bioorthogonal Chemistry Reactions in Living Cells | |
Lv, T; Wu, JB; Kang, FH; Wang, TT; Wan, BH; Lu, J.; Zhang, YH; Huang, ZJ
| |
| 2018-03-29 | |
| Source Publication | Organic letters
 |
| ISSN | 1523-7060 |
| Pages | 2164-2167 |
| Abstract | A class of O2-alkyl derived diazeniumdiolates 3a–f and 4a–c were designed and synthesized as new bioorthogonal NO precursors, which can be effectively uncaged in the presence of a palladium catalyst via bioorthogonal bond cleavage reactions to generate NO in living cancer cells, eliciting potent antiproliferative activity. |
| Keyword | N/a |
| Language | 英語English |
| The Source to Article | PB_Publication |
| Document Type | Journal article |
| Collection | University of Macau |
| Corresponding Author | Huang, ZJ |
| Recommended Citation GB/T 7714 | Lv, T,Wu, JB,Kang, FH,et al. Synthesis and Evaluation of O2‑Derived Diazeniumdiolates Activatable via Bioorthogonal Chemistry Reactions in Living Cells[J]. Organic letters, 2018, 2164-2167. |
| APA | Lv, T., Wu, JB., Kang, FH., Wang, TT., Wan, BH., Lu, J.., Zhang, YH., & Huang, ZJ (2018). Synthesis and Evaluation of O2‑Derived Diazeniumdiolates Activatable via Bioorthogonal Chemistry Reactions in Living Cells. Organic letters, 2164-2167. |
| MLA | Lv, T,et al."Synthesis and Evaluation of O2‑Derived Diazeniumdiolates Activatable via Bioorthogonal Chemistry Reactions in Living Cells".Organic letters (2018):2164-2167. |
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