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Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach.
Song, M.; Zhang, J.; Chan, G.; Hou, Y.; Chen, X. P.; Zhang, X.Q.; Ye, W.C.; Zhang, Q. W.
2020-11-30
Source PublicationJ Nat Prod
ISSN1520-6025
Volume83Pages:3502-3510
Abstract

Nine new limonoids, meliazedarines A-I (1-9), seven known analogues (10-16), and five known triterpenoids (17-21) were isolated from the fruits of Melia azedarach. Their structures were determined by analysis of 1D and 2D NMR, HRESIMS, X-ray diffraction, and electronic circular dichroism (ECD) data. Compound 7 showed significant cytotoxicity against the HCT116 cell line with IC50 values of 0.3 ± 0.1 μM.

KeywordLimonoids Triterpenoids Melia Azedarach
URLView the original
Language英語English
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorZhang, Q. W.
Recommended Citation
GB/T 7714
Song, M.,Zhang, J.,Chan, G.,et al. Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach.[J]. J Nat Prod, 2020, 83, 3502-3510.
APA Song, M.., Zhang, J.., Chan, G.., Hou, Y.., Chen, X. P.., Zhang, X.Q.., Ye, W.C.., & Zhang, Q. W. (2020). Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach.. J Nat Prod, 83, 3502-3510.
MLA Song, M.,et al."Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach.".J Nat Prod 83(2020):3502-3510.
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