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Genetic basis for conversion of rough-to-smooth colony morphology in Actinobacillus actinomycetemcomitans
Wang Y.; Liu A.; Chen C.
2005-06-01
Source PublicationInfection and Immunity
ISSN00199567
Volume73Issue:6Pages:3749-3753
Abstract

The basis of the rough-to-smooth conversion of Actinobacillus actinomycetemcomitans was examined. Smooth variants often contained mutations at the flp promoter region. Replacing the mutated flp promoter with the wild-type promoter restored the rough phenotype. The expression level of the flp promoter was ∼100-fold lower in smooth than in rough strains. Mutations of the flp promoter are a cause of the rough-to-smooth conversion. Copyright © 2005, American Society for Microbiology. All Rights Reserved.

DOI10.1128/IAI.73.6.3749-3753.2005
URLView the original
Language英語English
WOS IDWOS:000229485900063
Scopus ID2-s2.0-19744373475
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Citation statistics
Document TypeJournal article
CollectionUniversity of Macau
AffiliationUniversity of Southern California, School of Dentistry
Recommended Citation
GB/T 7714
Wang Y.,Liu A.,Chen C.. Genetic basis for conversion of rough-to-smooth colony morphology in Actinobacillus actinomycetemcomitans[J]. Infection and Immunity, 2005, 73(6), 3749-3753.
APA Wang Y.., Liu A.., & Chen C. (2005). Genetic basis for conversion of rough-to-smooth colony morphology in Actinobacillus actinomycetemcomitans. Infection and Immunity, 73(6), 3749-3753.
MLA Wang Y.,et al."Genetic basis for conversion of rough-to-smooth colony morphology in Actinobacillus actinomycetemcomitans".Infection and Immunity 73.6(2005):3749-3753.
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